Effects of Widely Used Heavy Metals on Embryological Development of Model Organism Zebrafish (Danio rerio)

Authors

  • Nejdet Gültepe Department of Fisheries Fundamental Sciences, Fisheries Faculty, Atatürk University, 25240 Erzurum, Turkey
  • Mousa S. M. Gaballah Veterinary Medicine Faculty, Omar Al-Mukhtar University, Al-Bayda, Libya
  • Riyam Ghazi Kareem Al-Sarray Department of Biotechnology, Faculty of Biotechnology, Al Qasim Green University, Babil, Iraq

DOI:

https://doi.org/10.58309/aajpas.v1i1.14

Keywords:

Embryo defect, deformity, malformation, toxicity, hatching time

Abstract

This study aimed to investigate the toxic effect of widely used heavy metals, which are KCN, CuSO4, K3Fe(CN)6, and FeClOH on the embryological development of model organism zebrafish (Danio rerio). Zebrafish embryos were exposed to these heavy metals at a concentration was 0.5 mg/L for 96 hpf (hours post-fertilization). Mortality, hatching, and malformation rates were examined during the exposure period. The result showed that FeClOH and K3Fe(CN)6 were toxic to zebrafish embryos and caused an increased mortality rate and delayed hatching. Moreover, FeClOH and K3Fe(CN)6 caused a lot of types of abnormalities while KCN and CuSO4 were more toxic to zebrafish embryos and caused a mortality rate, which was 100% at 24 hpf. In conclusion, this study showed that widely used heavy metals, such as KCN, CuSO4, FeCIOH, and K3Fe (CN)6 cause toxicity in embryos, delay hatching time and rate, and/or cause many different malformations.

Downloads

Published

2022-12-27

Issue

Vol. 1 No. 1 (2022)

Section

Articles

License

Copyright (c) 2022 Nejdet Gültepe, Mousa S. M. Gaballah, Riyam Ghazi Kareem Al-Sarray

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Articles Copyright Published by Al-Jabal Academy Journal of Pure and Applied Sciences (AAJPAS) is retained to the author(s), who grant AAJPAS a license to publish the article. Also they accept the article remains published by AAJPAS website (except in occasion of a retraction of the article). 

How to Cite

Effects of Widely Used Heavy Metals on Embryological Development of Model Organism Zebrafish (Danio rerio). (2022). Al-Jabal Academy Journal of Pure and Applied Sciences, 1(1), 29-40. https://doi.org/10.58309/aajpas.v1i1.14